Name | 4-Thiouridine |
Synonyms | NSC 518132 Thiouridine thiouridine 4-THIOURIDINE 4-Thiouridine THIOURIDINE, 4- 1-((2R,3R,4S,5R) 4-Thio-D-uridine Uridine, 4-thio- Thiouridine (VAN) 4-thiouridineapprox. -4-thioxo-3,4-dihydropyrimidin-2(1H) 1-pentofuranosyl-4-thioxo-3,4-dihydropyrimidin-2(1H)-one 1-beta-D-ribofuranosyl-4-thioxo-3,4-dihydropyrimidin-2(1H)-one 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxyMethyl)tetrahydrofuran-2-yl)-4-thioxo-3,4-dihydropyriMidin-2(1H)-one |
CAS | 13957-31-8 |
EINECS | 237-735-3 |
InChI | InChI=1/C9H12N2O5S/c12-3-4-6(13)7(14)8(16-4)11-2-1-5(17)10-9(11)15/h1-2,4,6-8,12-14H,3H2,(H,10,15,17) |
InChIKey | ZLOIGESWDJYCTF-XVFCMESISA-N |
Molecular Formula | C9H12N2O5S |
Molar Mass | 260.27 |
Density | 1.72±0.1 g/cm3(Predicted) |
Melting Point | 139-140℃ (ethanol ) |
Water Solubility | Soluble in water (20 mg/ml), and methanol (10 mg/ml). |
Solubility | Soluble in water (20 mg/ml), and methanol (10 mg/ml). |
Appearance | White to light yellow powder |
Color | light yellow |
pKa | 4.75±0.20(Predicted) |
Storage Condition | -20°C |
Refractive Index | 1.732 |
MDL | MFCD00006538 |
Use | 4-Thiouridine is a photoreactive (crosslinking) uridine analogue that upon phosphorylation to 4-thioUTP may be incorporated into RNA structures. 4-Thiouridine may be used to study the specificity and kinetics of uridine-cytidine kinases. |
Safety Description | 24/25 - Avoid contact with skin and eyes. |
WGK Germany | 3 |
HS Code | 29349990 |